Tag: exchangeability
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Amino acid exchangeability: condensing data from mutation-scanning experiments
I just had to post the image below because it’s so cool. Here’s the backstory. A decade ago, Lev Yampolsky and I did a meta-analysis of mutation-scanning experiments– studies that systematically change amino acids in proteins, and measure the effects. Based on about 10,000 experimental exchanges, we computed an “EX” measure…
Mutation and evolution 